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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CSK
All Species:
43.03
Human Site:
Y403
Identified Species:
78.89
UniProt:
P41240
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P41240
NP_001120662.1
450
50704
Y403
V
P
R
V
E
K
G
Y
K
M
D
A
P
D
G
Chimpanzee
Pan troglodytes
XP_001138005
450
50665
Y403
V
P
R
V
E
K
G
Y
K
M
D
A
P
D
G
Rhesus Macaque
Macaca mulatta
XP_001101430
450
50702
Y403
V
P
R
V
E
K
G
Y
K
M
D
A
P
D
G
Dog
Lupus familis
XP_853247
465
51967
Y418
V
P
R
V
E
K
G
Y
K
M
D
A
P
D
G
Cat
Felis silvestris
Mouse
Mus musculus
P41241
450
50595
Y403
V
P
R
V
E
K
G
Y
K
M
D
A
P
D
G
Rat
Rattus norvegicus
P32577
450
50728
Y403
V
P
R
V
E
K
G
Y
K
M
D
A
P
D
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P41239
450
50733
Y403
V
P
R
V
E
K
G
Y
K
M
D
P
P
D
G
Frog
Xenopus laevis
NP_001079062
450
50789
Y403
V
P
K
V
E
N
G
Y
K
M
D
A
P
D
G
Zebra Danio
Brachydanio rerio
NP_001071067
450
50999
Y403
V
P
R
V
E
K
G
Y
K
M
D
S
P
D
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_731611
1052
113728
Y1007
V
K
H
V
E
V
G
Y
K
M
E
A
P
E
G
Honey Bee
Apis mellifera
XP_393399
493
55500
Y444
V
K
C
V
E
K
G
Y
K
M
E
P
P
D
G
Nematode Worm
Caenorhab. elegans
NP_001021778
539
60138
G494
V
V
R
Y
I
E
K
G
Y
R
M
E
A
P
E
Sea Urchin
Strong. purpuratus
XP_795344
763
85563
E717
S
E
V
V
A
H
V
E
K
G
Y
R
M
E
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
99.7
95.4
N.A.
98.4
98.4
N.A.
N.A.
93.3
83.7
85.7
N.A.
26.6
48.2
43.4
36.8
Protein Similarity:
100
98.4
100
96.1
N.A.
99.3
99.7
N.A.
N.A.
95.3
90.4
93.1
N.A.
32.7
62.8
57.3
45.7
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
93.3
86.6
93.3
N.A.
66.6
73.3
13.3
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
93.3
93.3
100
N.A.
80
80
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
0
0
0
62
8
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
70
0
0
77
0
% D
% Glu:
0
8
0
0
85
8
0
8
0
0
16
8
0
16
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
85
8
0
8
0
0
0
0
85
% G
% His:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
16
8
0
0
70
8
0
93
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
85
8
0
8
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
70
0
0
0
0
0
0
0
0
0
16
85
8
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
70
0
0
0
0
0
0
8
0
8
0
0
0
% R
% Ser:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
93
8
8
93
0
8
8
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
85
8
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _